3T RESEARCH APPLICATIONS

MRI/S provides high contrast anatomical images and detailed physiological and biochemical information from human subjects non-invasively.  It is particularly well suited for the study of human disease processes and also for obtaining a better understanding of normal human behavior.
 

  • fMRI with a wide range of presentation protocols

  • Proton spectroscopy, single voxel, 2D and 3D with analysis

  • Diffusion imaging with fibre tracking capability

  • T1 and T2 Relaxation time measurements and analysis

  • MR Perfusion

  • Susceptibility Weighted Imaging

  • Whole cerebrum Myelin Water Imaging

 

 

1H MR spectrum from brain.
The peaks are related to concentrations of brain metabolites

WHAT WE DO

Lesions in multiple sclerosis brain

High Resolution Imaging

MRI provides superb anatomical detail due to its excellent soft tissue image contrast. Accurate measurements may be obtained for volumes of total brain, individual brain structures or lesions.

High resolution image of knee cartilage. Signal from yellow bone marrow can be suppressed to enable characterization of cartilage health in knee and hip joints.

Image of neuronal fibre tracts which cross between the brain hemispheres

The bright regions in the above images denote regions of brain activated when the subject carried out a simple finger tapping exercise

Image of diffusion anisotropy where nerve fibre direction is denoted by colour

Functional MRI (fMRI)

When neurons are activated, they cause a local change in oxygen concentration which can be detected by fMRI.  By synchronizing image collection with the accomplishment of a specific task, one can map out which regions of brain are involved with the task. For example, in Parkinson’s disease, fMRI is used to elucidate compensatory mechanisms which mask symptoms and/or delay clinical progression of the disease.

Diffusion Tensor Imaging (DTI)

Water in brain undergoes random motions which are influenced by the shape of the local environment. For example, in white matter, neuronal fibre tracts permit water to diffuse more readily along their long axes. DTI enables measurement of fibre tract direction in brain.